NFL

Study Estimates 75% of Deceased Former NFL Players Had CTE

  • Authored By: Sports Now
  • Updated Oct 29, 2026, 04:51 IST

A comprehensive study published in JAMA Network Open reveals that approximately 75% of former NFL players who passed away between 2008 and 2023 suffered from chronic traumatic encephalopathy, a neurodegenerative brain disease.

Study Estimates 75% of Deceased Former NFL Players Had CTE

A significant new study has shed light on the prevalence of chronic traumatic encephalopathy (CTE) among former professional football players. According to research published in JAMA Network Open, an estimated 75% of NFL players who died between 2008 and 2023 were found to have the neurodegenerative brain disease, which is frequently associated with high-impact sports.

The research, conducted by a team from Boston University, Mass General Brigham, and the Concussion & CTE Foundation, represents the most comprehensive effort to date to quantify the presence of CTE within this specific population. While the findings highlight a high prevalence, the authors noted that the data is limited to deceased individuals and cannot be used to predict the condition in living players, nor does it address the prevalence of the disease among college or youth football participants.

Methodology and Research Context

The study analyzed a total of 2,362 cases, integrating data from 396 brains donated for research with National Death Index records of 1,966 deceased players who did not donate. Researchers acknowledged that the donor group tended to be white, younger at the time of death, and had longer NFL careers compared to the non-donor group. Despite these variables, the study concluded that the prevalence of CTE remains high even when accounting for these differences.

CTE is currently only diagnosable post-mortem, and the disease is categorized into stages ranging from I to IV based on severity. The researchers pointed out that many of the identified cases may have been in the early stages at the time of death, potentially remaining symptom-free. Lead author Julia Gallini described the estimated 75% prevalence as concerning, emphasizing the urgent need for improved diagnostic tools for living patients and better support systems for affected families.

Industry Response and Future Outlook

The NFL responded to the publication by stating that the league remains committed to enhancing player safety through strategies aimed at reducing head impacts and concussions. The organization encouraged former players to access available health resources. Meanwhile, the NFL Players Association underscored the importance of such research, noting that these studies are vital for gaining a deeper understanding of the long-term health impacts associated with the sport.

While this study provides a clearer picture of CTE among former NFL athletes, researchers highlighted that significant gaps in data persist regarding lower levels of football. The lack of information on non-donors at the high school and collegiate levels continues to present a challenge for scientists aiming to understand the full scope of the disease across the sport.